abstract：:Experiment 1 investigated the effects of catecholaminergic deafferentation or cell body lesions of the amygdala on fear conditioning to explicit and contextual cues. Bilateral infusions of quinolinic acid mainly damaged neurons within the basolateral region of the amygdala. 6-Hydroxydopamine infusions at the same coor...

journal_title：Neuroscience

authors： Selden NR,Everitt BJ,Jarrard LE,Robbins TW

更新日期：1991-01-01 00:00:00

abstract：:When the neural tracer Fluoro-Gold is used to retrogradely label a population of axotomized neurons, cellular labeling can persist in the axotomized nucleus even when Nissl staining indicates that the injured neurons have degenerated. In order to determine the identity of the labeled cells that remain, this study comb...

journal_title：Neuroscience

authors： Rinaman L,Milligan CE,Levitt P

更新日期：1991-01-01 00:00:00

abstract：:The Ca(2+)-dependent release of the neurotransmitter glutamate from purified nerve terminals (synaptosomes) of the rat hippocampus was studied in a rapid perfusion apparatus. The response of the terminals was investigated with respect to the kinetics and duration of the release of endogenous glutamate upon brief and s...

journal_title：Neuroscience

authors： Verhage M,Lopes da Silva FH,Ghijsen WE

更新日期：1991-01-01 00:00:00

abstract：:Six-day-old neuronal cultures derived from 14-day-old embryonic rat cerebral hemispheres were highly enriched in GABAergic neurons, as was demonstrated by immunocytochemistry using an anti-glutamate decarboxylase antiserum. They contained about 64% glutamate decarboxylase-positive neurons. About 8% of these neurons pr...

journal_title：Neuroscience

authors： Deloulme JC,Gensburger C,Sarhan S,Seiler N,Sensenbrenner M

更新日期：1991-01-01 00:00:00

abstract：:The peripheral reorganization of pulpal nerves after tooth injury was studied, in the rat, with anterograde horseradish peroxidase tracing techniques, and combined retrograde Fluorogold tracing and immunohistochemistry was employed to examine the effects of inferior alveolar nerve lesions or tooth injury on some cytoc...

journal_title：Neuroscience

authors： Fried K,Arvidsson J,Robertson B,Pfaller K

更新日期：1991-01-01 00:00:00

abstract：:Using immunohistochemistry and in situ hybridization, we have analysed the distribution of vasoactive intestinal polypeptide (VIP) and peptide histidine isoleucine (PHI) in hypothalamus of male and female Sprague-Dawley rats under normal and experimental conditions. In most cases there was a good overlap between the d...

journal_title：Neuroscience

authors： Ceccatelli S,Fahrenkrug J,Villar MJ,Hökfelt T

更新日期：1991-01-01 00:00:00

abstract：:The purpose of this study was to experimentally investigate the applicability of the equilibrium-point hypothesis to the dynamics of single-joint movements. Subjects were trained to perform relatively slow (movement time 600-1000 ms) or fast (movement time 200-300 ms) single-joint elbow flexion movements against a con...

journal_title：Neuroscience

authors： Latash ML,Gottlieb GL

更新日期：1991-01-01 00:00:00

abstract：:Free radicals have been implicated in a number of pathological conditions. To evaluate the neurophysiological consequences of free radical exposure, slices of hippocampus isolated from guinea-pigs were exposed to hydrogen peroxide which reacts with tissue iron to generate hydroxyl free radicals. Long-term potentiation...

journal_title：Neuroscience

authors： Pellmar TC,Hollinden GE,Sarvey JM

更新日期：1991-01-01 00:00:00

abstract：:Locomotor stepping in the Nembutal-anesthetized rat was elicited by electrical stimulation of either of two sites in the right or left posterolateral hypothalamus. Essential midbrain loci were identified by reversibly blocking the elicited locomotion through local injections of the anesthetic procaine (15%, 0.5 microl...

journal_title：Neuroscience

authors： Levy DI,Sinnamon HM

更新日期：1990-01-01 00:00:00

abstract：:By means of antisera to cytoplasmic components of nerve fibres and neuropeptides which are known to be present in sensory or sympathetic nerves we have examined the distribution of both total and different types of nerve fibres in normal and inflamed human synovial tissue. Samples of synovia were obtained at surgery f...

journal_title：Neuroscience

authors： Mapp PI,Kidd BL,Gibson SJ,Terry JM,Revell PA,Ibrahim NB,Blake DR,Polak JM

更新日期：1990-01-01 00:00:00

abstract：:Using a semihorizontal section plane tangential to the ventral surface of the cerebral peduncle, the authors re-examined cyto-, myelo- and dendroarchitecture, acetylcholinesterase activity, afferent fibers, and efferent projection neurons of the substantia nigra pars reticulata. In the semihorizontal section plane, th...

journal_title：Neuroscience

authors： Tokuno H,Nakamura Y,Kudo M,Kitao Y

更新日期：1990-01-01 00:00:00

abstract：:Similarities in cellular morphology, afferentation, efferentation, and neurotransmitter content between the internal and external parts of the pallidum and the substantia nigra pars reticulata have long been noted. Here we present evidence that the globus pallidus, entopedunucular nucleus and substantia nigra pars ret...

journal_title：Neuroscience

authors： Sousa R,Hrinya Tannery N,Lafer EM

更新日期：1990-01-01 00:00:00

abstract：:Light and electron microscopic immunocytochemical methods were used to study the distribution and the morphology of substance P-positive fibers and axon terminals in the dorsal column nuclei of rats and cats, and to determine whether they are part of an ascending input to these nuclei. In rats, substance P-positive fi...

journal_title：Neuroscience

authors： Conti F,De Biasi S,Giuffrida R,Rustioni A

更新日期：1990-01-01 00:00:00

abstract：:The rat pineal gland is an attractive system for studies on the capacity of neural systems to recover following partial injury, allowing both for the creation of precise subtotal lesions and for the measurement of recovery of function at the cellular level. The pineal gland receives overlapping sympathetic innervation...

journal_title：Neuroscience

authors： Kuchel GA,Sherman RL,Zigmond RE

更新日期：1990-01-01 00:00:00

abstract：:Intracellular and extracellular recording techniques and in vitro preparation were used to examine the effect of [Met]enkephalin on the rat periaqueductal neurons. In the 20 cells that were recorded intracellularly, [Met]enkephalin caused an increase in the resting membrane conductance, hyperpolarization of the cell m...

journal_title：Neuroscience

authors： Behbehani MM,Jiang M,Chandler SD

更新日期：1990-01-01 00:00:00

abstract：:In order to determine which neurotransmitters and neuropeptides are utilized by the neurons of the mesencephalic trigeminal nucleus and by the fibres making synaptic contact with these primary sensory cells, we have set up an immunohistochemical study using antibodies against 17 major neurotransmitters and neuropeptid...

journal_title：Neuroscience

authors： Copray JC,Ter Horst GJ,Liem RS,van Willigen JD

更新日期：1990-01-01 00:00:00

abstract：:Several lines of evidence indicate that L-glutamate may be a neurotransmitter of fine myelinated and unmyelinated primary afferent fibres in the spinal cord. The aim of the present study was to determine if L-glutamate was enriched in the terminals of these fibres. We performed the post-embedding immunogold technique ...

journal_title：Neuroscience

authors： Maxwell DJ,Christie WM,Short AD,Storm-Mathisen J,Ottersen OP

更新日期：1990-01-01 00:00:00

abstract：:The distribution and origin of nerves with calcitonin gene-related peptide, substance P or neurokinin A immunoreactivity in the walls of the cerebral arteries were investigated in three microchiropteran species. The supply of nerves immunoreactive for substance P and neurokinin A to the bat cerebral arteries is confin...

journal_title：Neuroscience

authors： Ando K,Arai S,Kawamura K

更新日期：1990-01-01 00:00:00

abstract：:Fetal striatal neurons were transplanted into the ibotenic acid lesioned rat striatum. Three months after transplantation the grafted tissue was Golgi-impregnated and examined at the light microscopic level to determine the morphological characteristics of the transplanted neurons. Golgi-impregnated neurons were then ...

journal_title：Neuroscience

authors： Helm GA,Palmer PE,Bennett JP Jr

更新日期：1990-01-01 00:00:00

abstract：:This study was undertaken to investigate the effects of activating dopamine receptors in accumbens and prefrontal cortex on self-stimulation behavior in the medial forebrain bundle. The experiments were carried out in rats chronically implanted with one stimulating electrode in medial forebrain bundle and two bilatera...

journal_title：Neuroscience

authors： Olds ME

更新日期：1990-01-01 00:00:00

abstract：:The mechanism of neuropeptide secretion induced by bradykinin from capsaicin-sensitive afferents was studied in guinea-pig atria. Both the inotropic response induced by bradykinin (0.1 microM) in the electrically driven isolated guinea-pig left atria and the bradykinin (10 microM)-induced release of calcitonin gene-re...

journal_title：Neuroscience

authors： Geppetti P,Tramontana M,Santicioli P,Del Bianco E,Giuliani S,Maggi CA

更新日期：1990-01-01 00:00:00

abstract：:The solitary nucleus (nucleus tractus solitarii), the first central relay for taste in mammals, was studied anatomically and physiologically in the golden hamster (Mesocricetus auratus). Activity of neurons to anterior tongue stimulation with sucrose, NaCl and KCl were extracellularly recorded. Electrolytic lesions or...

journal_title：Neuroscience

authors： McPheeters M,Hettinger TP,Nuding SC,Savoy LD,Whitehead MC,Frank ME

更新日期：1990-01-01 00:00:00

abstract：:The rat brain and spinal cord have been mapped for Type II glucocorticoid receptor-like immunoreactivity in neurons and glia, using a monoclonal antibody, BUGR2, which recognizes an epitope close to the DNA-binding domain of the rat Type II receptor. The study revealed a widespread distribution of Type II-like immunor...

journal_title：Neuroscience

authors： Ahima RS,Harlan RE

更新日期：1990-01-01 00:00:00

abstract：:In animal models of transients ischemia, selective vulnerability and delayed neuronal death in the hippocampus have been extensively described. However, little is known about selective damage in the neocortex and the thalamus, even though deficits in sensorimotor function are common in humans surviving hypoxic/ischemi...

journal_title：Neuroscience

authors： Lin CS,Polsky K,Nadler JV,Crain BJ

更新日期：1990-01-01 00:00:00

abstract：:The termination pattern of septohippocampal axons visualized by anterograde transport of Phaseolus vulgaris leucoagglutinin was studied in the hippocampal formation in the rat, with special reference to the innervation of neurons immunoreactive for the neuroactive peptides cholecystokinin, somatostatin or vasoactive i...

journal_title：Neuroscience

authors： Gulyás AI,Görcs TJ,Freund TF

更新日期：1990-01-01 00:00:00

abstract：:A previously developed model of exercise-induced muscle contracture using iodoacetate to inhibit glyceraldehyde-3-phosphate dehydrogenase in rat hindlimb muscles produced selective type II myofiber damage. Utilizing a modification of the same model system, rats were given intra-aortic ortho-iodosobenzoic acid (700 nmo...

journal_title：Neuroscience

authors： Locklear I,Feeback DL,Brumback RA

更新日期：1990-01-01 00:00:00

abstract：:Direct intracerebral administration of N-methyl-D-aspartate typically produces focal brain injury. (+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-immi ne maleate (MK-801), a non-competitive N-methyl-D-aspartate antagonist, can protect against N-methyl-D-aspartate-mediated brain injury when administered sho...

journal_title：Neuroscience

authors： McDonald JW,Silverstein FS,Johnston MV

更新日期：1990-01-01 00:00:00

abstract：:Cholecystokinin binding sites were labeled with [3H]cholecystokinin-8, [125I]cholecystokinin-33, and [125I]cholecystokinin-8 in major structures of macaque basal ganglia by in vitro receptor autoradiography. Analysis of autoradiograms revealed areas of heavy cholecystokinin binding in the neostriatum and substantia ni...

journal_title：Neuroscience

authors： Kritzer MF,Innis RB,Goldman-Rakic PS

更新日期：1990-01-01 00:00:00

abstract：:Experimental animal studies have demonstrated a number of receptor localizations on specific cortical afferents and neurons. The present study of human posterior cingulate cortex evaluates the laminar distributions of particular receptors and their likely association with components of the neuropil. Coverslip autoradi...

journal_title：Neuroscience

authors： Vogt BA,Plager MD,Crino PB,Bird ED

更新日期：1990-01-01 00:00:00

abstract：:Previous work had shown that nicotinic antagonists resulted in a marked up-regulation of alpha-bungarotoxin sites in chromaffin cells in culture. The present experiments were done to determine the intracellular mechanism(s) whereby nicotinic antagonists might mediate their effects on these receptors. Chromaffin cells ...

journal_title：Neuroscience

authors： Geertsen S,Afar R,Trifaró JM,Quik M

更新日期：1990-01-01 00:00:00

abstract：:Rat cerebellar granule cells, when subjected to a glucose-free environment for 4 h, developed extensive degeneration of neuronal cell bodies and their associated neurite network over the following 24 h. This neuronal damage was quantitated with a colorimetric assay using the metabolic dye 3-(4,5-dimethylthiazol-2-yl)-...

journal_title：Neuroscience

authors： Facci L,Leon A,Skaper SD

更新日期：1990-01-01 00:00:00

abstract：:Two major systems of cholinergic projection neurons are found within the centrum of the mammalian brain: the basal nuclear complex, projecting predominantly to the cerebral cortex, amygdala, and hippocampus, and the pontomesencephalotegmental network, innervating primarily the thalamus. Neurons comprising the latter n...

journal_title：Neuroscience

authors： Consolo S,Bertorelli R,Forloni GL,Butcher LL

更新日期：1990-01-01 00:00:00

abstract：:The aim of the present study was to examine the fine structural changes in the superior cervical ganglion of adult rats following baclofen treatment. On the addition of this GABAB receptor agonist there was a transient increase in the number of coated vesicles and pits in the dendrites of principal sympathetic neurons...

journal_title：Neuroscience

authors： Parducz A,Joó F,Siklós L,Wolff JR

更新日期：1990-01-01 00:00:00

abstract：:Quantitative autoradiography of [3H]SCH 23390 and [3H](-)-sulpiride binding was performed in the brain of rats of various ages (3, 11 and 24 months) in order to study the changes in D1 and D2 receptor density with age. Binding of [3H]SCH 23390 in the caudate-putamen decreased progressively and markedly at rostral leve...

journal_title：Neuroscience

authors： Morelli M,Mennini T,Cagnotto A,Toffano G,Di Chiara G

更新日期：1990-01-01 00:00:00

abstract：:When adult dorsal root ganglion cells are dissociated and maintained in vitro, both the small dark and the large light neurons show increases in the growth-associated protein GAP-43, a membrane phosphoprotein associated with neuronal development and plasticity. Immunoreactivity for GAP-43 appears in the cytoplasm of t...

journal_title：Neuroscience

authors： Woolf CJ,Reynolds ML,Molander C,O'Brien C,Lindsay RM,Benowitz LI

更新日期：1990-01-01 00:00:00

abstract：:The cellular localization of preprosomatostatin mRNA in the rat brain and sensory ganglia has been examined in detail using a newly developed highly sensitive non-radioactive in situ hybridization histochemistry procedure. An alkaline phosphatase labelled anti-sense 30mer oligodeoxynucleotide probe was used for detect...

journal_title：Neuroscience

authors： Kiyama H,Emson PC

更新日期：1990-01-01 00:00:00

abstract：:The effect of intracranial microdialysis on brain glucose metabolism in control and kainic acid-treated rats was assessed by semi-quantitative [14C]2-deoxyglucose autoradiography. A dialysis fiber loop was implanted into the piriform cortex or a horizontal Vita fiber into the hippocampus, and 24 h later, fibers were p...

journal_title：Neuroscience

authors： Chastain JE Jr,Samson F,Nelson SR,Pazdernik TL

更新日期：1990-01-01 00:00:00

abstract：:A transient aberrant projection from the retina to the contralateral inferior colliculus was demonstrated in pigmented rats in both whole-brains and sections following intra-ocular injection of horseradish peroxidase. The projection was prominent on the day of birth but reached its maximum density and extent after inj...

journal_title：Neuroscience

authors： Cooper AM,Cowey A

更新日期：1990-01-01 00:00:00

abstract：:The functional roles of striatonigral neurokinins were studied by analysing the effects of intranigral injections of substance P and neurokinin A on the extracellular levels of dopamine and dihydroxyphenylacetic acid in the striatum, as measured by in vivo microdialysis in rats. An opioid antagonist, naloxone, and a G...

journal_title：Neuroscience

authors： Reid MS,Herrera-Marschitz M,Ungerstedt U

更新日期：1990-01-01 00:00:00

abstract：:Carbachol, a long-acting cholinergic agonist, was microinjected (4 micrograms/250 nl per 90 s) into 90 sites within the anterodorsal pontine tegmentum of four cats and the time to onset and percentage of time spent in a desynchronized sleep-like state during 40 min postinjection were calculated. Compared with more pos...

journal_title：Neuroscience

authors： Yamamoto K,Mamelak AN,Quattrochi JJ,Hobson JA

更新日期：1990-01-01 00:00:00